Morphofunctional features very similar to humans. Humans, nothing is known regarding the closest relatives ofĪpes (or Hominoidea) are a small group of primates with By comparison with the rich information on High altitude usually include data on the subjects’ Hct, Hb, orīoth as indicators of the polycythemic response to high altitude residence. Inįact, studies concerned with any form of human adaptation to Has found support in a myriad of observations and is comprehensively summarized in many book chapters (e.g., This notion, originated by Viault (1890) and Muntz (1891) andĮxpanded by Barcroft et al. In humans is the increase in red blood cells or hematocrit (Hct) and in hemoglobin concentration (Hb). Ne of the hallmarks of permanence at high altitudes The Democratic Republic of Congo with a habitat range between 29 m altitude (Rothman et al., 2007). Gorilla, the Eastern mountain gorilla (Gorilla beringeiīeringei), which totals less than 1000 individuals in the wild Ī small group of these lives in the Virunga National Park of The only exception is one subspecies of the Eastern Nonhuman apes have evolved and live at sea level or lowland Least 10,000 years (Aldenderfer, 2003), from the AndeanĪltiplano of South America to the Tibetan Plateau in AsiaĪnd the Ethiopian Highlands in East Africa. The lack of information regarding nonhuman apes at altitude is explained by the fact that humans have been the onlyĪpes to spread out and colonize high altitude regions for at Of DNA base pairs with some members of this group (HoyerĮt al., 1972 Britten, 2002 Fujiyama et al., 2002 Prüfer One of the great apes and share an extremely high percentage Respectively, Hominidae and Hylobatidae) with four generaĮach and, respectively, 6 and 17 species. Keywords: altitude adaptation chimpanzee gibbon gorilla hematology orangutan siamang Represent the exception among apes rather than the rule.
Polycythemia is not aĬommon response to altitude hypoxia and, at least at moderate altitudes, the degree of the human response may We conclude that lack of, or minimal, hematopoietic response to moderateĪltitude can occur in mammalian species that are not genetically adapted to high altitudes. AtĮither altitude in the group of nonhuman apes, the increase in Hct was much less than in humans, and that of Hb In Hct or Hb was apparent at 1500 m at 2000 m, the increase was significant only for the Hb of females. Women were significantly higher than at sea level at the 1500 bin (1250–1750 m) hence, the altitude thresholdįor the human hematological responses must be between 10 m. These human data were binned for 0–250 mĪltitude (sea level) and for each 500 m of progressively higher altitudes.
The human altitude profiles of Hct and Hbīetween sea level and 3000 m were constructed from a compilation of literature sources that (all combined)Ĭomprised data sets of 10,000–12,000 subjects for each gender. Data were collected from 29 specimens of 7 species of apes at 2073 m altitude (barometric pressure Pb = 598 mm Hg) additional data originatedįrom apes located at a lower altitude (1493 m, Pb = 639 mm Hg). Hematologic response (increase in hematocrit and in blood hemoglobin concentration ) of humans toĪltitude hypoxia was shared by our closest relatives, the nonhuman apes. High Alt Med Biol 00:000–000, 2016.-We asked to what extent the Hematocrit and hemoglobin levels of nonhuman apes at moderateĪltitudes: a comparison with humans. Hematocrit and Hemoglobin Levels of NonhumanĪpes at Moderate Altitudes: A Comparison with Humans
0 kommentar(er)
